Quarterly report pursuant to Section 13 or 15(d)

Financial Instruments (Details)

v2.4.0.6
Financial Instruments (Details) (USD $)
In Thousands, unless otherwise specified
Jun. 30, 2012
Dec. 31, 2011
Quoted Prices in Active Markets for Identical Assets (Level 1) [Member]
   
Liabilities:    
Liabilities, Current portion, contingent value rights - CyDex      
Quoted Prices in Active Markets for Identical Assets (Level 1) [Member] | Current portion of liability for contingent value rights - CyDex [Member]
   
Liabilities:    
Liabilities, Current portion, contingent value rights - CyDex     
Quoted Prices in Active Markets for Identical Assets (Level 1) [Member] | Liability for contingent value right - Neurogen [Member]
   
Liabilities:    
Liabilities, Current portion, contingent value rights - CyDex     
Quoted Prices in Active Markets for Identical Assets (Level 1) [Member] | Liability for contingent value right-CyDex [Member]
   
Liabilities:    
Liabilities, Current portion, contingent value rights - CyDex     
Fair Value Measurements [Member]
   
Liabilities:    
Liabilities, Current portion, contingent value rights - CyDex 14,152 18,312
Fair Value Measurements [Member] | Current portion of liability for contingent value rights - CyDex [Member]
   
Liabilities:    
Liabilities, Current portion, contingent value rights - CyDex 3,739 6,879
Fair Value Measurements [Member] | Liability for contingent value right-Metabasis [Member]
   
Liabilities:    
Liabilities, Current portion, contingent value rights - CyDex   1,068
Fair Value Measurements [Member] | Liability for contingent value right - Neurogen [Member]
   
Liabilities:    
Liabilities, Current portion, contingent value rights - CyDex 500 700
Fair Value Measurements [Member] | Liability for contingent value right-CyDex [Member]
   
Liabilities:    
Liabilities, Current portion, contingent value rights - CyDex 9,913 9,665
Fair Value Measurements [Member] | Short-term investments [Member]
   
Assets:    
Assets, Short-term investments 1,500 10,000
Fair Value Measurements [Member] | Quoted Prices in Active Markets for Identical Assets (Level 1) [Member]
   
Liabilities:    
Liabilities, Current portion, contingent value rights - CyDex   1,068
Fair Value Measurements [Member] | Quoted Prices in Active Markets for Identical Assets (Level 1) [Member] | Liability for contingent value right-Metabasis [Member]
   
Liabilities:    
Liabilities, Current portion, contingent value rights - CyDex   1,068
Fair Value Measurements [Member] | Quoted Prices in Active Markets for Identical Assets (Level 1) [Member] | Short-term investments [Member]
   
Assets:    
Assets, Short-term investments 1,500 10,000
Fair Value Measurements [Member] | Significant Other Observable Inputs (Level 2) [Member]
   
Liabilities:    
Liabilities, Current portion, contingent value rights - CyDex      
Fair Value Measurements [Member] | Significant Other Observable Inputs (Level 2) [Member] | Current portion of liability for contingent value rights - CyDex [Member]
   
Liabilities:    
Liabilities, Current portion, contingent value rights - CyDex      
Fair Value Measurements [Member] | Significant Other Observable Inputs (Level 2) [Member] | Liability for contingent value right-Metabasis [Member]
   
Liabilities:    
Liabilities, Current portion, contingent value rights - CyDex      
Fair Value Measurements [Member] | Significant Other Observable Inputs (Level 2) [Member] | Liability for contingent value right - Neurogen [Member]
   
Liabilities:    
Liabilities, Current portion, contingent value rights - CyDex      
Fair Value Measurements [Member] | Significant Other Observable Inputs (Level 2) [Member] | Liability for contingent value right-CyDex [Member]
   
Liabilities:    
Liabilities, Current portion, contingent value rights - CyDex      
Fair Value Measurements [Member] | Significant Other Observable Inputs (Level 2) [Member] | Short-term investments [Member]
   
Assets:    
Assets, Short-term investments      
Fair Value Measurements [Member] | Significant Unobservable Inputs (Level 3) [Member]
   
Liabilities:    
Liabilities, Current portion, contingent value rights - CyDex 14,152 17,244
Fair Value Measurements [Member] | Significant Unobservable Inputs (Level 3) [Member] | Current portion of liability for contingent value rights - CyDex [Member]
   
Liabilities:    
Liabilities, Current portion, contingent value rights - CyDex 3,739 6,879
Fair Value Measurements [Member] | Significant Unobservable Inputs (Level 3) [Member] | Liability for contingent value right-Metabasis [Member]
   
Liabilities:    
Liabilities, Current portion, contingent value rights - CyDex      
Fair Value Measurements [Member] | Significant Unobservable Inputs (Level 3) [Member] | Liability for contingent value right - Neurogen [Member]
   
Liabilities:    
Liabilities, Current portion, contingent value rights - CyDex 500 700
Fair Value Measurements [Member] | Significant Unobservable Inputs (Level 3) [Member] | Liability for contingent value right-CyDex [Member]
   
Liabilities:    
Liabilities, Current portion, contingent value rights - CyDex 9,913 9,665
Fair Value Measurements [Member] | Significant Unobservable Inputs (Level 3) [Member] | Short-term investments [Member]
   
Assets:    
Assets, Short-term investments