Quarterly report pursuant to Section 13 or 15(d)

Basis of Presentation (Details 1)

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Basis of Presentation (Details 1) (USD $)
In Thousands, unless otherwise specified
3 Months Ended 6 Months Ended
Jun. 30, 2012
Jun. 30, 2011
Jun. 30, 2012
Jun. 30, 2011
Basis of Presentation [Line Items]        
Share- based compensation expense Total $ 1,394 $ 1,221 $ 2,103 $ 1,690
Research and Development Expense [Member]
       
Basis of Presentation [Line Items]        
Share- based compensation expense Total 523 405 948 512
General and administrative expenses [Member]
       
Basis of Presentation [Line Items]        
Share- based compensation expense Total $ 871 $ 816 $ 1,155 $ 1,178