Quarterly report pursuant to Section 13 or 15(d)

Basis of Presentation (Details 1)

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Basis of Presentation (Details 1) (USD $)
In Thousands, unless otherwise specified
3 Months Ended 9 Months Ended
Sep. 30, 2012
Sep. 30, 2011
Sep. 30, 2012
Sep. 30, 2011
Basis of Presentation [Line Items]        
Share-based compensation expense total $ 1,013 $ 950 $ 3,116 $ 2,646
Research and development expense [Member]
       
Basis of Presentation [Line Items]        
Share-based compensation expense total 263 300 1,211 808
General and administrative expenses [Member]
       
Basis of Presentation [Line Items]        
Share-based compensation expense total $ 750 $ 650 $ 1,905 $ 1,838