Quarterly report pursuant to Section 13 or 15(d)

Significant Accounting Policies (Accounting for Share-Based Compensation) (Details)

v3.5.0.2
Significant Accounting Policies (Accounting for Share-Based Compensation) (Details) - USD ($)
$ in Thousands
3 Months Ended 6 Months Ended
Jun. 30, 2016
Jun. 30, 2015
Jun. 30, 2016
Jun. 30, 2015
Basis of Presentation [Line Items]        
Share-based compensation expense total $ 4,647 $ 3,760 $ 8,766 $ 6,675
Research and development expenses        
Basis of Presentation [Line Items]        
Share-based compensation expense total 2,089 1,253 3,674 2,174
General and administrative expenses        
Basis of Presentation [Line Items]        
Share-based compensation expense total $ 2,558 $ 2,507 $ 5,092 $ 4,501