Quarterly report pursuant to Section 13 or 15(d)

Significant Accounting Policies (Property and Equipment) (Details)

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Significant Accounting Policies (Property and Equipment) (Details) - USD ($)
$ in Thousands
Jun. 30, 2016
Dec. 31, 2015
Summary of Property and equipment    
Property and equipment , gross $ 2,684 $ 3,153
Less accumulated depreciation and amortization (1,503) (2,781)
Total property and equipment, net 1,181 372
Lab and office equipment    
Summary of Property and equipment    
Property and equipment , gross 1,063 2,248
Leasehold improvements    
Summary of Property and equipment    
Property and equipment , gross 929 273
Computer equipment and software    
Summary of Property and equipment    
Property and equipment , gross $ 692 $ 632