Ligand to Ring Opening Bell at NASDAQ Stock Market Ceremony

SAN DIEGO--

Ligand Pharmaceuticals Incorporated (NASDAQ:LGND) today announced that John L. Higgins, President and CEO along with the executive management team and Board of Directors will ring the NASDAQ stock market opening bell on Wednesday, September 26 at 9:30 a.m. EDT. "We are thrilled to open the NASDAQ bell as it represents the launch of the new Ligand. I would like to recognize the Ligand employees for their hard work and dedication to rebuilding the business and to our shareholders for their continued support," said John L. Higgins.

Where:    NASDAQ MarketSite
          Broadcast Studio
          4 Times Square, 43rd & Broadway

Webcast:  A live webcast of the NASDAQ Opening Bell will be available
           at: http://www.nasdaq.com/reference/marketsite_about.stm.

About Ligand Pharmaceuticals

Ligand discovers and develops new drugs that address critical unmet medical needs of patients in the areas of thrombocytopenia, hepatitis C, cancer, hormone-related diseases, osteoporosis and inflammatory diseases. Ligand's proprietary drug discovery and development programs are based on its leadership position in gene transcription technology, primarily related to intracellular receptors.

Source: Ligand Pharmaceuticals Incorporated

Released September 25, 2007