Annual report pursuant to Section 13 and 15(d)

Balance Sheet Account Details - Property and Equipment (Details)

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Balance Sheet Account Details - Property and Equipment (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Property, Plant and Equipment [Line Items]      
Property and equipment , gross $ 6,074 $ 3,390  
Less accumulated depreciation and amortization (1,862) (1,571)  
Property and equipment, net 4,212 1,819  
Depreciation expense 400 200 $ 200
Lab and office equipment      
Property, Plant and Equipment [Line Items]      
Property and equipment , gross 3,460 1,067  
Leasehold improvements      
Property, Plant and Equipment [Line Items]      
Property and equipment , gross 1,917 1,754  
Computer equipment and software      
Property, Plant and Equipment [Line Items]      
Property and equipment , gross $ 697 $ 569  
Minimum      
Property, Plant and Equipment [Line Items]      
Property and equipment, useful life 3 years    
Maximum      
Property, Plant and Equipment [Line Items]      
Property and equipment, useful life 10 years