Annual report pursuant to Section 13 and 15(d)

Lease Obligations - Operating Lease Obligations and Payments (Details)

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Lease Obligations - Operating Lease Obligations and Payments (Details)
$ in Thousands
12 Months Ended
Dec. 31, 2017
USD ($)
Payments expected to received from sublease agreements  
Operating lease obligation, Less than 1 year $ 1,375
Operating lease obligation, 1-2 years 1,701
Operating leases obligation, 3-4 years 619
Operating lease obligation, Thereafter 50
Operating lease obligation, Total 3,745
Operating lease obligation, Less than 1 year, net 734
Operating lease obligation, 1-2 years, net 1,340
Operating lease obligation, 3-4 years, net 619
Operating lease obligation, Thereafter, net 50
Operating lease obligation, net, Total $ 2,743
Corporate headquarters-San Diego, CA | California  
Payments expected to received from sublease agreements  
Lease Termination Date Apr. 30, 2023
Operating lease obligation, Less than 1 year $ 131
Operating lease obligation, 1-2 years 275
Operating leases obligation, 3-4 years 291
Operating lease obligation, Thereafter 50
Operating lease obligation, Total $ 747
Office and research facility-La Jolla, CA | California  
Payments expected to received from sublease agreements  
Lease Termination Date Jun. 30, 2019
Operating lease obligation, Less than 1 year $ 737
Operating lease obligation, 1-2 years 373
Operating leases obligation, 3-4 years 0
Operating lease obligation, Thereafter 0
Operating lease obligation, Total 1,110
Sublease payments expected to be received, Less than 1 year 641
Sublease payments expected to be received, 1-2 years 361
Sublease payments expected to be received, 3-4 years 0
Sublease payments expected to be received, Thereafter 0
Sublease payments expected to be received, Total $ 1,002
Bioscience and Technology Business Center-Lawrence, KS | Kansas  
Payments expected to received from sublease agreements  
Lease Termination Date Dec. 01, 2020
Operating lease obligation, Less than 1 year $ 57
Operating lease obligation, 1-2 years 113
Operating lease obligation, Total $ 170
Office - Emeryville, CA | California  
Payments expected to received from sublease agreements  
Lease Termination Date Aug. 01, 2021
Operating lease obligation, Less than 1 year $ 253
Operating lease obligation, 1-2 years 528
Operating leases obligation, 3-4 years 186
Operating lease obligation, Total $ 967
Research Facility - Emeryville, CA | California  
Payments expected to received from sublease agreements  
Lease Termination Date Aug. 01, 2021
Operating lease obligation, Less than 1 year $ 197
Operating lease obligation, 1-2 years 412
Operating leases obligation, 3-4 years 142
Operating lease obligation, Total $ 751