Exhibit 21.1

LIGAND PHARMACEUTICALS INCORPORATED

LIST OF SUBSIDIARIES

Name		Jurisdiction of Incorporation
Glycomed Incorporated		California
Allergan Ligand Retinoid Therapeutics, Inc.		Delaware
Ligand Pharmaceuticals International, Inc.		Delaware
Ligand Biopharmaceuticals, Incorporated		Delaware
Ligand JVR, Inc.		Delaware
Seragen Incorporated		Delaware
Seragen Technology, Inc.		Delaware
Pharmacopeia, LLC		Delaware
Metabasis Therapeutics, Inc.		Delaware
Neurogen Corporation		Delaware
CyDex Pharmaceuticals, Inc.		Delaware
Open Monoclonal Technology, Inc.		Delaware
OMT I, Inc.		Delaware
OMT I, Inc.		Delaware
Crystal		California