Quarterly report pursuant to Section 13 or 15(d)

Fair Value Measurements - Assets and Liabilities Measured at Fair Value on Recurring Basis (Details)

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Fair Value Measurements - Assets and Liabilities Measured at Fair Value on Recurring Basis (Details)
$ in Thousands
 1 Months Ended 3 Months Ended
Jan. 31, 2010
contingent_value_right
Mar. 31, 2023
USD ($)
Dec. 31, 2022
USD ($)
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Number of CVR Series | contingent_value_right 4    
Transferred over Time | Phase 3 clinical trial      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Gross contract asset   $ 10,000  
Maximum | Transferred over Time | Development, regulatory, & commercial milestones and tiered royalties      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Investments   375,000  
Metabasis      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Number of CVRs issued per acquiree share | contingent_value_right 4    
Number of CVRs issued from each CVR series | contingent_value_right 1    
Frequency of cash payments to CVR holders 6 months    
Mark-to-market adjustment of CVR liability   (700)  
Recurring      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Investment in Viking common stock   59,359 $ 63,122
Total assets   193,937 166,864
Amounts owed to former licensor   44 44
Total liabilities   2,887 3,557
Recurring | Short-term investments, excluding Viking      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Investments, fair value   134,578 103,742
Recurring | Contingent liabilities | CyDex      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Contingent liabilities   86 84
Recurring | Contingent liabilities | Metabasis      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Contingent liabilities   2,757 3,429
Recurring | Level 1      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Investment in Viking common stock     63,122
Total assets   67,212 67,114
Amounts owed to former licensor   44 44
Total liabilities   44 44
Recurring | Level 1 | Short-term investments, excluding Viking      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Investments, fair value   7,853 3,992
Recurring | Level 1 | Contingent liabilities | CyDex      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Contingent liabilities   0 0
Recurring | Level 1 | Contingent liabilities | Metabasis      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Contingent liabilities   0 0
Recurring | Level 2      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Investment in Viking common stock   0 0
Total assets   126,592 99,615
Amounts owed to former licensor   0 0
Total liabilities   2,757 3,429
Recurring | Level 2 | Short-term investments, excluding Viking      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Investments, fair value   126,592 99,615
Recurring | Level 2 | Contingent liabilities | CyDex      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Contingent liabilities   0 0
Recurring | Level 2 | Contingent liabilities | Metabasis      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Contingent liabilities   2,757 3,429
Recurring | Level 3      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Investment in Viking common stock   0 0
Total assets   133 135
Amounts owed to former licensor   0 0
Total liabilities   86 84
Recurring | Level 3 | Short-term investments, excluding Viking      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Investments, fair value   133 135
Recurring | Level 3 | Contingent liabilities | CyDex      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Contingent liabilities   86 84
Recurring | Level 3 | Contingent liabilities | Metabasis      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Contingent liabilities   $ 0 $ 0