Annual report pursuant to Section 13 and 15(d)

Stockholders' Equity - Narrative (Details)

v3.22.4
Stockholders' Equity - Narrative (Details) - USD ($)
1 Months Ended 12 Months Ended
Jun. 30, 2022
Sep. 30, 2019
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Sep. 30, 2022
Corporate Share Repurchase            
Stock repurchase program, authorized amount   $ 500,000,000        
Stock repurchase program, period in force   3 years        
Shares repurchased in period (shares)         934,079  
Shares repurchased in period     $ 0 $ 0 $ 77,998,000  
At-The Market Equity Offering            
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]            
Sale of stock, authorized offering amount           $ 100,000,000
Stock options            
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]            
Weighted-average grant date fair value per share of stock options (USD per share)     $ 28.90 $ 80.08 $ 41.39  
Intrinsic value of options exercised     $ 4,600,000 $ 77,300,000 $ 11,900,000  
Cash received from options exercised     $ 2,600,000 $ 33,000,000 $ 2,500,000  
2002 Stock Incentive Plan | Stock options            
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]            
Increase the number of shares under the 2002 Stock Incentive Plan (shares) 1,000,000          
Shares available for future option grants (shares)     1,300,000      
Unrecognized compensation cost     $ 32,700,000      
Weighted-average period in which cost is expected to be recognized     2 years 8 months 12 days      
2002 Stock Incentive Plan | Restricted stock            
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]            
Weighted-average period in which cost is expected to be recognized     1 year 8 months 12 days      
Unrecognized compensation cost, restricted stock     $ 12,400,000      
Amended ESPP            
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]            
Shares available for future option grants (shares)     35,881      
Employee Stock Purchase Plan            
Shares allowed to purchase in employee stock purchase plan per employee (shares)     1,250      
Proportion of fair market value of common stock at which stock is purchased under ESPP (as a percent)     85.00%      
Common stock issued under amended ESSP (shares)     8,479 8,448 6,455  
Omniab Separation | Stock options            
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]            
Unrecognized compensation cost     $ 4,800,000      
Weighted-average period in which cost is expected to be recognized     1 year 9 months 18 days      
Omniab Separation | Restricted stock            
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]            
Weighted-average period in which cost is expected to be recognized     1 year      
Unrecognized compensation cost, restricted stock     $ 1,200,000