Quarterly report pursuant to Section 13 or 15(d)

Basis of Presentation and Summary of Significant Accounting Policies - Accounting for Share-Based Compensation (Details)

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Basis of Presentation and Summary of Significant Accounting Policies - Accounting for Share-Based Compensation (Details) - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2022
Mar. 31, 2021
Basis of Presentation [Line Items]    
Share-based compensation expense $ 9,044 $ 8,405
SBC - Research and development expenses    
Basis of Presentation [Line Items]    
Share-based compensation expense 3,914 3,939
SBC - General and administrative expenses    
Basis of Presentation [Line Items]    
Share-based compensation expense $ 5,130 $ 4,466