Quarterly report pursuant to Section 13 or 15(d)

Basis of Presentation and Summary of Significant Accounting Policies - Accounting for Share-Based Compensation (Details)

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Basis of Presentation and Summary of Significant Accounting Policies - Accounting for Share-Based Compensation (Details) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2020
Sep. 30, 2019
Sep. 30, 2020
Sep. 30, 2019
Basis of Presentation [Line Items]        
Share-based compensation expense $ 7,740 $ 6,297 $ 20,752 $ 18,215
SBC - Research and development expenses        
Basis of Presentation [Line Items]        
Share-based compensation expense 3,094 2,481 8,510 7,136
SBC - General and administrative expenses        
Basis of Presentation [Line Items]        
Share-based compensation expense $ 4,646 $ 3,816 $ 12,242 $ 11,079