Quarterly report pursuant to Section 13 or 15(d)

Basis of Presentation and Summary of Significant Accounting Policies - Narrative (Details)

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Basis of Presentation and Summary of Significant Accounting Policies - Narrative (Details)
1 Months Ended 3 Months Ended 9 Months Ended
Dec. 31, 2018
USD ($)
Sep. 30, 2020
USD ($)
position
$ / shares
shares
Jun. 30, 2020
USD ($)
Sep. 30, 2019
USD ($)
shares
Sep. 30, 2020
USD ($)
position
$ / shares
shares
Sep. 30, 2019
USD ($)
shares
Jan. 01, 2020
USD ($)
Dec. 31, 2019
USD ($)
Property, Plant and Equipment [Line Items]                
Accounting Standards Update         us-gaap:AccountingStandardsUpdate201613Member      
Revenue recognized from milestone method revenue   $ 5,800,000   $ 1,000,000.0 $ 8,300,000 $ 5,000,000.0    
Fair value of equity securities   $ 6,581,000     $ 6,581,000     $ 9,910,000
Number of positions in an unrealized loss position | position   2     2      
Credit losses related to available-for-sale debt securities   $ 0     $ 0      
Additional allowance for credit losses recorded related to COVID-19   $ (100,000)     200,000      
Allowance for credit loss             $ 5,500,000  
Increase (decrease) to allowance for credit loss during period         $ 500,000      
Potentially dilutive shares excluded from calculation due to anti-dilutive effect (shares) | shares   7,028,000   11,549,000 8,330,000 8,694,000    
Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction, Start Date [Axis]: 2020-10-01                
Property, Plant and Equipment [Line Items]                
Expected timing of satisfaction of remaining performance obligation   3 years     3 years      
Warrants                
Property, Plant and Equipment [Line Items]                
Fair value of equity securities   $ 155,000     $ 155,000     125,000
Warrants | Short-term Investments                
Property, Plant and Equipment [Line Items]                
Fair value of equity securities   $ 6,600,000     $ 6,600,000     9,900,000
Share-based Compensation                
Property, Plant and Equipment [Line Items]                
Potentially dilutive shares excluded from calculation due to anti-dilutive effect (shares) | shares   700,000   700,000 650,000      
Adjustment                
Property, Plant and Equipment [Line Items]                
Cumulative-effect adjustment from adoption of ASU 2016-13, net of tax               (5,200,000)
Viking Therapeutics, Inc.                
Property, Plant and Equipment [Line Items]                
Warrant exercise price (USD per share) | $ / shares   $ 1.50     $ 1.50      
Viking Therapeutics, Inc. | Common Stock | Short-term Investments                
Property, Plant and Equipment [Line Items]                
Fair value of equity securities   $ 33,900,000     $ 33,900,000     48,400,000
Palvella                
Property, Plant and Equipment [Line Items]                
Revenue recognized from milestone method revenue     $ 3,000,000.0          
Royalty Agreements | Aziyo                
Property, Plant and Equipment [Line Items]                
Effective interest rate for forecasted cash flows (as a percent)         23.00%      
Commercial license rights                
Property, Plant and Equipment [Line Items]                
Up-front payment   38,298,000     $ 38,298,000     38,298,000
Commercial license rights | Palvella                
Property, Plant and Equipment [Line Items]                
Contract asset $ 8,000,000.0              
Up-front payment $ 10,000,000.0 $ 10,000,000     $ 10,000,000     $ 10,000,000
Minimum | Royalty Agreements | Palvella                
Property, Plant and Equipment [Line Items]                
Royalty rate (as a percent) 5.00%              
Maximum | Viking Therapeutics, Inc.                
Property, Plant and Equipment [Line Items]                
Outstanding warrants to purchase shares of Viking's common stock (shares) | shares   1,500,000     1,500,000      
Maximum | Royalty Agreements | Palvella                
Property, Plant and Equipment [Line Items]                
Royalty rate (as a percent) 9.80%