Quarterly report pursuant to Section 13 or 15(d)

Fair Value Measurements - Assets and Liabilities at Fair Value (Details)

v3.19.1
Fair Value Measurements - Assets and Liabilities at Fair Value (Details) - USD ($)
$ in Thousands
Mar. 31, 2019
Dec. 31, 2018
Assets:    
Short-term investments $ 1,383,083 $ 647,408
Investment in warrants 13,233 9,257
Total assets 1,396,316 656,665
Liabilities:    
Amounts owed to former licensor 147 199
Total liabilities 13,768 12,741
Transferred over Time | Phase 3 Clinical Trial    
Liabilities:    
Contract asset 10,000  
Maximum | Transferred over Time | Development, Regulatory, & Commercial Milestones and Tiered Royalties    
Liabilities:    
Investments 375,000  
Crystal    
Liabilities:    
Contingent liabilities 4,976 6,477
CyDex    
Liabilities:    
Contingent liabilities 464 514
Metabasis    
Liabilities:    
Contingent liabilities 8,181 5,551
Level 1    
Assets:    
Short-term investments 67,458 47,517
Investment in warrants 12,723 9,257
Total assets 80,181 56,774
Liabilities:    
Amounts owed to former licensor 147 199
Total liabilities 147 199
Level 1 | Crystal    
Liabilities:    
Contingent liabilities 0 0
Level 1 | CyDex    
Liabilities:    
Contingent liabilities 0 0
Level 1 | Metabasis    
Liabilities:    
Contingent liabilities 0 0
Level 2    
Assets:    
Short-term investments 1,315,625 599,891
Investment in warrants 0 0
Total assets 1,315,625 599,891
Liabilities:    
Amounts owed to former licensor 0 0
Total liabilities 0 5,551
Level 2 | Crystal    
Liabilities:    
Contingent liabilities 0 0
Level 2 | CyDex    
Liabilities:    
Contingent liabilities 0 0
Level 2 | Metabasis    
Liabilities:    
Contingent liabilities 0 5,551
Level 3    
Assets:    
Short-term investments 0 0
Investment in warrants 510 0
Total assets 510 0
Liabilities:    
Amounts owed to former licensor 0 0
Total liabilities 13,621 6,991
Level 3 | Crystal    
Liabilities:    
Contingent liabilities 4,976 6,477
Level 3 | CyDex    
Liabilities:    
Contingent liabilities 464 514
Level 3 | Metabasis    
Liabilities:    
Contingent liabilities $ 8,181 $ 0