Annual report pursuant to Section 13 and 15(d)

Business Combinations - Narrative (Details)

v3.10.0.1
Business Combinations - Narrative (Details)
1 Months Ended 12 Months Ended
Oct. 06, 2017
USD ($)
numberOfCollaborationAgreements
Jan. 08, 2016
USD ($)
Oct. 31, 2018
USD ($)
Dec. 31, 2018
USD ($)
Dec. 31, 2017
USD ($)
Business Acquisition [Line Items]          
Revenue royalty payable on all Cydex-related revenue (as a percent)         20.00%
Cydex-related revenue amount that triggers royalty payments         $ 15,000,000.0
Finite-lived intangible asset, useful life       20 years  
Goodwill       $ 86,646,000 $ 85,959,000
Vernalis          
Business Acquisition [Line Items]          
Gross payments to acquire business     $ 43,000,000.0    
Projected cash flow discount rate (as a percent)     34.00%    
Goodwill     $ 3,740,000    
Crystal          
Business Acquisition [Line Items]          
Gross payments to acquire business $ 27,200,000        
Working capital adjustment 2,200,000        
Total share consideration 10,500,000        
Cash payable to Crystal Shareholders 336,000     $ 200,000  
Fair value of contingent consideration 8,401,000        
Goodwill $ 10,697,000        
OMT          
Business Acquisition [Line Items]          
Gross payments to acquire business   $ 96,006,000      
Total share consideration   77,373,000      
Goodwill   59,969,000      
Consideration transferred   $ 173,400,000      
Core Technology | Vernalis          
Business Acquisition [Line Items]          
Finite-lived intangible asset, useful life     9 years    
Core Technology | Crystal          
Business Acquisition [Line Items]          
Projected cash flow discount rate (as a percent) 10.80%        
Average cash flow discount rate (as a percent) 4.60%        
Finite-lived intangible asset, useful life 20 years        
Core Technology | OMT          
Business Acquisition [Line Items]          
Projected cash flow discount rate (as a percent)   15.50%      
Finite-lived intangible asset, useful life   20 years      
Threshold of Revenues above $15 million with Three Collaboration Agreements | Crystal          
Business Acquisition [Line Items]          
Revenue royalty payable on all Cydex-related revenue (as a percent) 10.00%        
Cydex-related revenue amount that triggers royalty payments $ 15,000,000        
Threshold of Revenues above $1.5 million with Four Collaboration Agreements | Crystal          
Business Acquisition [Line Items]          
Revenue royalty payable on all Cydex-related revenue (as a percent) 20.00%        
Cydex-related revenue amount that triggers royalty payments $ 1,500,000        
Number of collaboration agreements | numberOfCollaborationAgreements 4