Annual report pursuant to Section 13 and 15(d)

Summary of Significant Accounting Policies (Details Textual)

v3.6.0.2
Summary of Significant Accounting Policies (Details Textual)
12 Months Ended
Dec. 31, 2016
USD ($)
Dec. 31, 2015
USD ($)
Dec. 31, 2014
USD ($)
Jan. 31, 2010
right
Basis of Presentation [Line Items]        
Working capital deficit $ 64,100,000      
Mezzanine equity excluded from working capital deficit $ 30,000,000      
Days after threshold consecutive trading days to complete payment of principal 3 days      
Number of consecutive trading days 50 days      
Maturity period of cash and cash equivalents, maximum 3 months      
Write-downs related to obsolete inventory $ 0 $ 0    
Goodwill impairment 0      
Royalty revenue 59,423,000 38,194,000 $ 29,994,000  
Accounts receivable, net $ 14,700,000 6,170,000    
Restocking fee (percent) 20.00%      
Share-based Compensation [Abstract]        
Expected dividend rate (percent) 0.00%      
Gain on disposition of product line $ 1,100,000      
Provision for taxes on gain $ 408,000 $ 0 $ 0  
Stock Options | 2002 Stock Incentive Plan        
Share-based Compensation [Abstract]        
Award expiration period 10 years      
Stock Options | Vest 1/8 on the six month anniversary of the date of grant | 2002 Stock Incentive Plan        
Share-based Compensation [Abstract]        
Award vesting period 6 months      
Award vesting right percentage 12.50%      
Stock Options | Vest 1/48 each month for forty-two months | 2002 Stock Incentive Plan        
Share-based Compensation [Abstract]        
Award vesting period 42 months      
Award vesting right percentage 2.08%      
Director        
Basis of Presentation [Line Items]        
Mr. Aryeh's ownership percentage in CorMatrix (percent, less than) 1.00%      
Director | 2002 Stock Incentive Plan        
Share-based Compensation [Abstract]        
Award vesting period 1 year      
Minimum        
Basis of Presentation [Line Items]        
Property and equipment, useful life 3 years      
Sales/revenues from partners reporting period 30 days      
Maximum        
Basis of Presentation [Line Items]        
Property and equipment, useful life 10 years      
Sales/revenues from partners reporting period 60 days      
Metabasis Therapeutics        
Basis of Presentation [Line Items]        
Number of contingent value rights | right       4
IPR&D        
Basis of Presentation [Line Items]        
Impairment charge $ 0      
CorMatrix        
Basis of Presentation [Line Items]        
Royalty revenue 1,500,000      
Accounts receivable, net $ 200,000